Vanderbilt University
Institute of Imaging Science
VUIIS Logo
Friday
22
September
2017
1:00pm
Robert Gould, PhD
Vanderbilt University
How multimodal neuroimaging technologies can provide innovative approaches for the treatment of Substance Use Disorders    (more ...)
How multimodal neuroimaging technologies can provide innovative approaches for the treatment of Substance Use Disorders    (hide ...)

Substance Use Disorder (SUD) remains a large public health problem worldwide that contributes to negative consequences at individual, familial, local community and global levels. Neuroimaging studies have been crucial in establishing that drug addiction is a disorder of the brain and is reflected by the recent change in nomenclature from ?drug abuse or addiction? to ?Substance Use Disorder? in the DSM-V. A brief overview of groundbreaking human and animal studies will be presented demonstrating that habitual and repeated drug use, despite negative consequences is, in fact a brain disorder. Although understanding the pathophysiological effects of chronic drug use is informative, drug treatments for SUD?s are relatively ineffective (for opioid, alcohol and nicotine use) and there remains no FDA-approved treatments for cocaine use disorder. Developing treatments for SUDs requires an understanding of 1) the underlying neurobiological changes caused by repeated drug use; 2) alterations that occur during abstinence following chronic drug use; and, 3) how putative pharmacological or psychosocial treatments affect underlying pathophysiology and future behavior. Ongoing animal studies will be described that focus on developing new treatments for multiple aspects of cocaine use disorder by examining novel pharmacological agents in classic animal models of drug addiction paired with functional magnetic resonance imaging (fMRI) in awake animals.
VUIIS Friday Seminar Series, MRB III Lecture Hall (Room 1220)
Friday
29
September
2017
Friday
06
October
2017
1:00pm
Nellie Byun, PhD
Research Instructor, VUIIS
TBA
Friday
13
October
2017
1:00pm
Jim Delikatny, Ph.D.
Perelman School of Medicine University of Pennsylvania
TBD
Friday
20
October
2017
1:00pm
Bruce Damon, PhD
Associate Professor, VUIIS
TBA
Friday
27
October
2017
1:00pm
Catie Chang, PhD
Advanced MRI, NIH
TBA
Friday
03
November
2017
Friday
10
November
2017
1:00pm
Zhaohua Ding, PhD
Associate Professor, VUIIS
TBA
Friday
17
November
2017
1:00pm
Eric Skaar, PhD, MPH
Ernest W. Goodpasture Professor of Pathology, VU
TBA
Friday
24
November
2017
Friday
01
December
2017
1:00pm
Richard Dortch, PhD
Research Assistant Professor, VUIIS
TBA
Friday
08
December
2017
1:00pm
Mark Does
Professor of BME, Electrical Engineering, Radiology
TBA