Vanderbilt University
Institute of Imaging Science

William Grissom, Ph.D.

Assistant Professor of Biomedical Engineering
Lab Website

Contact Information

(615) 322-6009


My research interests include RF pulse design for MRI (particularly parallel excitation), MRI for guided interventions (particularly high-intensity focused ultrasound (HIFU) surgery), and more generally fast algorithms, inverse problems, and optimization.


Members of my group are currently working on improving RF system calibrations such as mapping of the RF transmit field, advanced patient-tailored RF pulse designs for mitigating the effects of B1 and B0 field inhomogeneities, improved temperature reconstruction methods for guiding HIFU surgery, and ultrasound autofocusing algorithms using MR imaging feedback.


W A Grissom, M M Khalighi, L I Sacolick, B K Rutt, and M W Vogel. Small-tip-angle spokes pulse design using interleaved greedy and local optimization methods. Magn Reson Med, In Press, March 2012.

W A Grissom, G C McKinnon, and M W Vogel. Nonuniform and multidimensional Shinnar-Le Roux RF pulse design method. Magn Reson Med, In Press, September 2011.

W A Grissom, L I Sacolick, and M W Vogel. Invited review article: Improving high field magnetic resonance imaging using parallel excitation. Imaging in Medicine, 2(6):675-693, 2010.

W A Grissom, A B Kerr, P Stang, G C Scott, and J M Pauly. Minimum envelope roughness pulse design for reduced amplifier distortion in parallel excitation. Magn Reson Med, 64(5):1433-1440, 2010.

W A Grissom, V Rieke, A B Holbrook, Y Medan, M Lustig, J M Santos, M V McConnell, and K B Pauly. Hybrid referenceless and multibaseline subtraction MR thermometry for monitoring thermal therapies in moving organs. Med Phys, 37(9):5014-5026, 2010.