Vanderbilt University
Institute of Imaging Science

Mike Nickels, Ph.D.

Technical Director of the PET Radiochemistry Research Laboratories, Radiology and Radiological Sciences

Contact Information
(615) 343-5484


My research involves the development of new and novel radiopharmaceuticals and the necessary labeling techniques used to incorporate radionuclides.


I am currently investigating the use of microfluidic chemistry as a means to accomplish fluorine-18 labeling on both model compounds and authentic radiopharmaceutical agents.  I am also undertaking the synthesis of several new agents for imaging with fluorine-18 and carbon-11.


Nickels, M.; Xie, P.; Cobb, J.; Gore, J.; Pham, W. Functionalization of Iron Oxide   Nanoparticles with a Versatile Epoxy Amine Linker Journal of Materials Chemistry, 2010, 20, 4776-4780.  

Nolting, D.; Nickels, M.; Price, R.; Gore, J.; Pham, W. Synthesis of Bicyclo[5.3.0]Azulene   Derivatives?? Nature Protocols, 2009, 4(8), 1113-1117.  

Nickels, M.L.; Lee, B.C.; Katzenellenbogen, J.A.  Synthesis of 2-(18F)Fluoroestradiol For   Imaging of ER+ Tumors.  Journal of Labelled Compounds and Radiopharmaceuticals, 2007, 50 (S1), S161.  

Nickels, M.L.; Kim, S.H.; Katzenellenbogen, J.A.  Novel TACN Complexes as Estrogen   Receptor Ligands for Tumor Imaging Journal of Labelled Compounds and  Radiopharmaceuticals, 2007, 50 (S1), S239.