Vanderbilt University
Institute of Imaging Science
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Jackie Hill, Ph.D.

Postdoctoral Fellow

Contact Information

jacqueline.e.hill@vanderbilt.e

Interests

I'm interested in the synthesis of photosensitizers for the photodynamic therapy of cancer.

Projects

My current research is focused on the synthesis of a caged tamoxifen compound utilizing upconverting nanoparticles to be used for in vivo studies of colorectal cancer. I am also working on the synthesis of fluorescent probes to be used in fluorescence imaging.

Publications

Novel Selenorhodamine Dyes as Photosensitizers in Extracorporeal Photopheresis. Hill, J.E.; Kryman, M.W.; Schamerhorn, G.A.; Detty, M.R.; McIver, Z.A., Book of Abstracts, 27th European Colloquium on Heterocyclic Chemistry, Amsterdam, The Netherlands, July 3-6, 2016, P021.

A Comparative Study of the Photophysics of Phenyl, Thienyl, and Chalcogen Substituted Rhodamine Dyes. Sabatini, R.P.; Mark, M.F.; Mark, D.J.; Kryman, M.W.; Hill, J.E.; Brennessel, W.W.; Detty, M.R.; Eisenberg, R.; McCamant, D.W., Photochemical and Photobiological Sciences, 2016, 15 (11), 1417-1432.

Targeting T Cell Bioenergetics by Modulating P-Glycoprotein Selectively Depletes Alloreactive T Cells to Prevent Graft-versus-Host Disease. McIver, Z.A.; Grayson, J.M.; Coe, B.N.; Hill, J.E.; Schamerhorn, G.A.; Ohulchanskyy, T.Y.; Linder, M.K.; Davies, K.D.; Weiner, R.S.; Detty, M.R., Journal of Immunology, 2016, 197 (5), 1631- 1641.

Selective Photodepletion of Malignant T Cells in Extracorporeal Photopheresis with Selenorhodamine Photosensitizers.McIver, Z.A.; Kryman, M.W.; Choi, Y.; Coe, B.N.; Schamerhorn, G.A.; Linder, M.K.; Davies, K.S.; Hill, J.E.; Sawada, G.A.; Grayson, J.M.; Detty, M.R., Bioorganic and Medicinal Chemistry, 2016, 24 (17), 3918-3931.

Methods and Compounds for Phototherapy with Chalcogenorhodamine Photosensitizers. McIver, Z.A.; Hill, J.E.; Detty, M.R., 2015, Patent Number:WO 2015187940.