My research uses MR imaging-based approaches to non-invasively study biomechanical systems and to extract biomechanical information for understanding the systems and related pathologies.
1. Designing blood flow paths for an artificial kidney device using computational fluid dynamics (CFD) simulations and MRI validation.
2. Using MRI techniques to study the relationship between structure and function in leg muscle for future applications of monitoring progression of Becker muscular dystrophy and for assessing treatment efficacy.
3. Investigating the relationship between cerebral artery hemodynamics and stroke in patients with sickle cell disease using MRI in conjunction with CFD models.
AK Wake, JN Oshinski, AR Tannenbaum, DP Giddens. "Choice of in vivo versus idealized velocity boundary conditions influences physiologically relevant flow patterns in a subject-specific simulation of flow in the human carotid bifurcation," Journal of Biomechanical Engineering. 131(2):021013, 2009.
BM Damon, AKW Buck, Z Ding. "Diffusion-tensor MRI-based skeletal muscle fiber tracking," Imaging Medicine 3(6):675-687, 2011.
BM Damon, T Towse, AKW Buck, K Li, N Bryant, Z Ding, JH Park. "Quantitative Structural and Functional MRI of Skeletal Muscle," In: Muftuler T (Ed.) Quantitative Morphology and Physiology of the Human Body using MRI. London: Taylor and Francis Press, in press.