My research includes the evaluation of new molecular probes for cancer imaging, and studying the effects of new drugs on signal pathways and apoptosis of cancer cells. I have worked on cancer research at Vanderbilt University since 1998.
Ongoing research projects include the development and validation of new molecular imaging probes for cancer imaging, evaluation of the effects of small-molecules on molecular signaling pathways, and imaging in animal models that include receptor expression, proliferation, angiogenesis, and apoptosis.
Schulte ML, Fu A, Zhao P, Li J, Geng L, Smith ST, Kondo J, Coffey RJ, Johnson MO, Rathmell JC, Sharick JT, Skala MC, Smith JA, Berlin J, Washington MK, Nickels ML, Manning HC., Pharmacological blockade of ASCT2-dependent glutamine transport leads to antitumor efficacy in preclinical models. Nat Med. 2018 Jan 15. doi: 10.1038/nm.4464.
Buck JR, McKinley ET, Fu A, Abel TW, Thompson RC, Chambless L, Watchmaker JM, Harty JP, Cooper MK, Manning HC., Preclinical TSPO Ligand PET to Visualize Human Glioma Xenotransplants: A Preliminary Study. PLoS One. 2015 Oct 30;10(10):e0141659. doi: 10.1371/journal.pone.0141659.
Wang H, Yan H, Fu A, Han M, Hallahan D, Han Z., TIP-1 translocation onto the cell plasma membrane is a molecular biomarker of tumor response to ionizing radiation. PLoS One. 2010 Aug 11;5(8):e12051. doi: 10.1371/journal.pone.0012051.
Han Z, Fu A, Wang H, Diaz R, Geng L, Onishko H, Hallahan DE., Noninvasive assessment of cancer response to therapy. Nat Med. 2008 Mar;14(3):343-9. doi: 10.1038/nm1691. Epub 2008 Feb 24.