I am interested in the development of small-molecule radiotracers for molecular imaging that target neuroinflammation.
I am responsible for the production of clinical and research radiotracers.
PET Imaging Study of S1PR1 Expression in a Rat Model of Multiple Sclerosis. H Liu, H Jin, X Yue, Z Luo, C Liu, AJ Rosenberg, Z Tu. Molecular Imaging and Biology, 1-9
A promising carbon-11-labeled sphingosine-1-phosphate receptor 1-specific PET tracer for imaging vascular injury. H Jin, H Yang, H Liu, Y Zhang, X Zhang, AJ Rosenberg, Y Liu, S Lapi, T Z. Journal of Nuclear Cardiology
A potent and selective C-11 labeled PET tracer for imaging sphingosine-1-phosphate receptor 2 in the CNS demonstrates sexually dimorphic expression. X Yue, J H., H Liu, AJ Rosenberg, RS Klein, Z Tu. Organic and Biomolecular Chemistry 13, 7928-7939
A practical process for the preparation of [32P]S1P and binding assay for S1P receptor ligands. AJ Rosenberg, H Liu, Z Tu. Applied Radiation and Isotopes 102, 5-9
Synthesis of Imidazo [4, 5-b] pyridines and Imidazo [4, 5-b] pyrazines by Palladium Catalyzed Amidation of 2-Chloro-3-amino-heterocycles. AJ Rosenberg, J Zhao, DA Clark. Organic letters 14 (7), 1764-1767