I work in the field of hyperpolarized magnetic resonance imaging developing low field NMR equipment and polarizers for use in drug discovery, early detection and treatment of cancer, increased MRI sensitivity, and real time metabolic imaging.
Current projects include developing H/X NMR probe for in situ detection of hyperpolarized tracers for quality assurance, automation of the current 13C polarizer, automating parahydrogen production, aiding in equipment development for use in hyperpolarized xenon experiments, and developing a 15N polarizer.
Waddell KW, Coffey AM, Chekmenev EY - In Situ Detection of PHIP at 48 mT: Demonstration Using a Centrally Controlled Polarizer - J Am Chem Soc. 2011 Jan 12;133(1):97-101. Epub 2010 Dec 9.
Chen I, Coffey AM, Ding S, Dumpuri P, Dawant BM, Thompson RC, Miga MI - Intraoperative Brain Shift Compensation: Accounting for Dural Septa - IEEE Trans Biomed Eng. 2010 Nov 22. [Epub ahead of print]
Coffey A, Miga M, Garg I, Thompson R - An evaluative tool for preoperative planning of brain tumor resection - SPIE Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling Conference, Vol 7625, 2010
Garg I, Ding S, Coffey AM, Dumpuri P, Thompson RC, Dawant BM, Miga MI - Enhancement of subsurface brain shift model accuracy: a preliminary study - SPIE Medical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling Conference, Vol 7625, 2010